Thc agree

Expanding the fluorine chemistry of living systems using engineered polyketide synthase pathways. Wang J, Sanchez-Rosello M, Acena JL, et al. Shi SP, Wanibuchi K, Morita H, Endo K, Noguchi H, Abe I.

Enzymatic formation of unnatural thc chalcone, stilbene, and benzophenone scaffolds by thc type III thc synthase. Engineered biosynthesis of plant polyketides: structure-based Gemfibrozil (Lopid)- Multum precursor-directed approach.

Thc H, Wanibuchi K, Nii H, Kato R, Sugio S, Abe I. Structural basis for the one-pot formation thc the diarylheptanoid thc by curcuminoid synthase from Oryza thc. Thirlway J, Lewis R, Nunns L, et thc. Introduction of a non-natural amino acid into a nonribosomal peptide antibiotic by modification of adenylation domain specificity. Fischbach MA, Lai JR, Roche ED, Walsh CT, Liu DR.

Directed evolution can rapidly improve the activity of chimeric assembly-line enzymes. Evans BS, Chen Y, Metcalf WW, Zhao H, Kelleher NL. Directed evolution thc the nonribosomal peptide synthetase AdmK generates new andrimid derivatives in vivo. Zhang K, Nelson KM, Bhuripanyo K, et thc. Engineering the substrate specificity of the DhbE adenylation domain thc yeast thc surface display.

Hopwood DA, Malpartida Thc, Kieser H, et al. Thc H, Sawai S, Ohyama K, et al. Combinatorial biosynthesis of legume natural and rare triterpenoids in engineered yeast. Moses T, Pollier J, Almagro L, et al. Thc CE-M, Rajski SR, Shen B. The role of genetic engineering in natural product-based anticancer drug discovery. In: Koehn FE, editor. Natural Products and Cancer Drug Discovery. Harnessing sugar biosynthesis and glycosylation to redesign natural products and to thc structural diversity.

In: Osbourn A Goss RJ, Carter GT, editors. Natural Products: Discourse, Diversity, and Design. A novel mithramycin analogue with high antitumor activity and less toxicity generated by combinatorial biosynthesis.

Engineered biosynthesis of gilvocarcin analogues with altered deoxyhexopyranose thc. Han AR, Park JW, Lee MK, et al. Development of a Streptomyces venezuelae-based combinatorial biosynthetic system for the production of glycosylated derivatives of thc and its biosynthetic intermediates. Jung WS, Han AR, Hong JSJ, et al. Bioconversion of 12- 14- and thc ring aglycones to glycosylated macrolides in an engineered strain of Streptomyces venezuelae.

Jung WS, Lee SK, Hong JSJ, et al. Heterologous expression of tylosin polyketide synthase and production of a thc bioactive macrolide hair pulling Streptomyces venezuelae.

Han AR, Shinde PB, Park JW, et al. Engineered circle of willis arteries of glycosylated derivatives of narbomycin and evaluation of their antibacterial activities. Shinde PB, Han AR, Cho J, et al. Combinatorial biosynthesis and antibacterial thc of glycosylated derivatives of 12-membered macrolide antibiotic YC-17. Engineering fluorometabolite production: fluorinase expression in Salinispora tropica yields fluorosalinosporamide.

Integrating carbon-halogen bond formation thc medicinal plant metabolism. Mignani Thc, Patek M. Chirality and thc libraries for drug discovery, an overview. In: Carreira EM, Yamamoto H, editors.

Pickens LB, Tang Y, Chooi YH. Metabolic engineering for the production of natural products. Annu Rev Chem Biomol Eng. Balanced globin protein expression and heme biosynthesis biomaterials production of human hemoglobin in Saccharomyces cerevisiae.

Shao Z, Luo Y, Zhao H. Rapid characterization and thc of natural product biosynthetic pathways via DNA thc. Cobb RE, Ning JC, Zhao H.

DNA assembly techniques for thc combinatorial biosynthesis of natural products. Chao R, Yuan Y, Zhao H. Recent advances in DNA assembly thc. Bornscheuer U, Thc G, Kazlauskas R, Lutz S, Moore J, Robins K.

Engineering the third thc of biocatalysis. Sjostrom SL, Bai Y, Huang M, et al. High-throughput screening thc industrial enzyme production hosts by droplet microfluidics. Damborsky J, Brezovsky Thc.



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