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Views The birth of Rilpivirine Tablets (Edurant)- FDA Constraint Theory (TCT) started with an innocent querywhat optimizes the glass forming tendency of a meltand led to the finding that such melts possess an ideal connectivity, i.

The birth of Topological Constraint Theory (TCT) started with an innocent querywhat optimizes the glass forming tendency of a meltand led to the finding that such melts possess an Rilpivirine Tablets (Edurant)- FDA connectivity, i.

Complex disordered molecular networks are viewed as composed of structural trusses, wherein nodes (atoms) are connected to each other by mechanical constraints (chemical bonds). The approach worked well for sulfide reggie johnson selenide glasses, but was next extended to include Tellurides and modified Oxides by inclusion of dangling ends and temperature-dependent constraints using Molecular Dynamics (MD) simulations.

In the laboratory, these developments came to the fore once the recognition emerged that IP melts are super-strong in the fragile-strong classification, and lead to delayed homogenization of all melt compositions. The observation of rather abrupt rigidity- and stress-elastic phase transitions in dry and homogeneous glasses is consistent with their percolative nature.

The scope of this Research Topic includes understanding the flexible, intermediate, and stressed-rigid Topological phases of network glasses, and correlating these to respective melt dynamics using Rigidity Theory, MD simulations and statistical mechanics. Experiments designed around select material systems have not only served as test systems for validating theory, but have also opened a doorway to new materials with applications for Rilpivirine Tablets (Edurant)- FDA technologies.

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