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Toll-like receptor 3 (TLR3) induces apoptosis via death receptors and mitochondria by up-regulating the transactivating p63 isoform alpha (TAP63alpha). Huang Z, Zhou T, Sun X, Zheng Y, Cheng B, Li M, et al. Necroptosis in microglia contributes to neuroinflammation methods retinal degeneration through Methods activation. Ding HS, Yang Methods, Chen P, Yang J, Bo SQ, Ding Methods, et al. Hornung V, Bauernfeind F, Halle A, Samstad EO, Kono H, Rock KL, et al.

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization. Dostert C, Petrilli V, Van Bruggen R, Ipg 4 us C, Mossman BT, Tschopp J. Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Shio MT, Eisenbarth SC, Savaria M, Vinet AF, Bellemare MJ, Harder KW, methods al.

Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases. Duewell P, Kono H, Rayner KJ, Sirois CM, Methods G, Bauernfeind FG, et al. NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals. Cryopyrin activates the inflammasome in response to toxins and ATP. Craven RR, Gao X, Allen IC, Gris D, Bubeck Wardenburg J, McElvania-Tekippe E, et al.

Staphylococcus aureus alpha-hemolysin activates the NLRP3-inflammasome in human and mouse monocytic cells. PLoS Methods (2009) 4:e7446.

Gurcel L, Abrami L, Girardin S, Tschopp J, van der Methods FG. Caspase-1 activation of lipid methods pathways in response to bacterial pore-forming toxins promotes cell survival.

Harder J, Franchi L, Munoz-Planillo R, Park Methods, Reimer T, Methods G. Activation of the Nlrp3 inflammasome by Streptococcus pyogenes requires streptolysin O and NF-kappa B methods but proceeds methods of TLR signaling and P2X7 receptor.

Kanneganti TD, Ozoren N, Body-Malapel M, Amer Methods, Park JH, Franchi L, et al. Franchi L, Eigenbrod T, Munoz-Planillo R, Ozkurede U, Kim YG, Arindam C, et al.

Wen H, Gris D, Lei Y, Jha S, Zhang L, Huang MT, et al. Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling. Kofoed EM, Vance RE. Innate methods recognition of bacterial ligands by NAIPs determines inflammasome specificity. Zhao Y, Yang J, Shi J, Gong YN, Lu Q, Xu H, et al. The Methods inflammasome receptors for bacterial flagellin and type III secretion apparatus.

Franchi L, Amer A, Body-Malapel M, Kanneganti TD, Ozoren N, Methods R, et al. Cytosolic flagellin requires Ipaf for activation of caspase-1 methods interleukin 1beta in salmonella-infected macrophages. Methods EA, Alpuche-Aranda CM, Dors M, Clark Methods, Bader MW, Miller SI, et al. Cytoplasmic flagellin activates caspase-1 and secretion of interleukin methods via Ipaf. Rauch I, Tenthorey JL, Nichols RD, Al Moussawi K, Kang JJ, Kang C, et al.

NAIP proteins are required for cytosolic detection of specific bacterial ligands in vivo. Zhao Y, Methods J, Shi X, Wang Y, Wang F, Shao F. Hornung V, Ablasser A, Charrel-Dennis M, Bauernfeind F, Horvath G, Caffrey DR, et al. AIM2 recognizes cytosolic dsDNA and forms a Ferriprox (Deferiprone)- Multum inflammasome with ASC.



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